Page 40 - 《中国药房》2021年10期
P. 40
[ 7 ] LEE H E,KIM D H,PARK S J,et al. Neuroprotective ef- TrkB signaling pathway in a rat model of Alzheimer’s di-
fect of sinapic acid in a mouse model of amyloid β 1-42 pro- sease[J]. J Cell Physiol,2018,233(7):5281-5292.
tein-induced Alzheimer’s disease[J]. Pharmacol Biochem [20] EREMENKO E,MITTAL K,BERNER O,et al. BDNF-
Behav,2012,103:260-266. producing,amyloid β-specific CD4 T cells as targeted
[ 8 ] KIM D H,YOON B H,JUNG W Y,et al. Sinapic acid at- drug-delivery vehicles in Alzheimer’s disease[J]. EBio-
tenuates kainic acid-induced hippocampal neuronal da- Medicine,2019,43:424-434.
mage in mice[J]. Neuropharmacology,2010,59(1/2):20- [21] LUO L,LIU X L,LI J,et al. Macranthol promotes hippo-
30. campal neuronal proliferation in mice via BDNF-TrkB-
[ 9 ] NUMAKAWA T,SUZUKI S,KUMAMARU E,et al. PI3K/AKT signaling pathway[J]. Eur J Pharmacol,2015,
BDNF function and intracellularsignaling in neurons[J]. 762:357-363.
Histol Histopathol,2010,25(2):237-258. [22] ZIELINSKI M R,KRUEGER J M. Sleep and innate im-
[10] GIRARDET C,LENBRUN B,CABIROL-POL M,et al. munity[J]. Front Biosci(Schol Ed),2011,3:632-642.
Brain-derived neurotrophic factor/TrkB signaling regu- [23] ZHENG H,NIU S,ZHAO H,et al. Donepezil improves
lates daily astroglial plasticity in the suprachiasmatic nu- the cognitive impairment in a tree shrew model of Alz-
cleus:electron-microscopic evidence in mouse[J]. GLIA, heimer’s disease induced by amyloid-β 1-40 via activating
2013,61(7):1172-1177. the BDNF/TrkB signal pathway[J]. Metab Brain Dis,
[11] GANDY S. The role of cerebral amyloid β accumulation 2018,33(6):1961-1974.
in common forms of Alzheimer disease[J]. J Clin Invest, [24] MAYNARD K R,KARDIAN A,HILL J L,et al. TrkB sig-
2005,115(5):1121-1129. naling influences gene expression in cortistatin-expressing
interneurons[J]. eNeuro,2020,7(1):310-319.
[12] KRISHTAL J,BRAGINA O,METSLA K,et al. In situ fi-
[25] 张誉丹,袁德培,毛剑琴.基于BDNF/TrkB/CREB 途径探
brillizing amyloid-beta1-42 induces neurite degeneration
讨固本健脑液改善 AD 大鼠海马区神经元损伤的内在
and apoptosis of differentiated SH-SY5Y cells[J]. PLoS
机制[J].中药材,2020,43(9):2232-2237.
One,2017,12(10):e0186636.
[26] LIU L,ZHANG R,LIU K,et al. Tissue kallikrein protect
[13] ZHANG J,ZHEN Y F,REN P B C,et al. Salidroside at-
scortical neurons against in vitro ischemia-acidosis/reper-
tenuates beta amyloid-induced cognitive deficits via
fusion-induced injury through the ERK1/2 pathway[J].
modulating oxidative stress and inflammatory mediators
Exp Neurol,2009,219(2):453-465.
in rat hippocampus[J]. Behav Brain Res,2013,244:70-81.
[27] EASTON J B,ROYER A R,MIDDLEMAS D S. The pro-
[14] 张乐国,朱翠敏,吴强,等. β-淀粉样蛋白 1-42与颈部动脉
tein tyrosinephosphatase,SHP2,is required for the com-
粥样硬化及轻度认知障碍的相关性研究[J].世界复合医
plete activation of the RAS/MAPK pathway by brain-de-
学,2019,5(5):19-21.
rived neurotrophic factor[J]. J Neurochem,2006,97(3):
[15] 张照阳,范立华,蔡庆春. Hcy、淀粉样蛋白、TNF 水平变
834-845.
化在阿尔茨海默病中的表达及意义[J].实验与检验医
[28] PANDYA C D,KUTIYANAWALLA A,PILLAI A. BDNF-
学,2019,37(5):925-927.
TrkB signaling and neuroprotection in schizophrenia[J].
[16] CHEN Y J,HUANG X B,CHEN W Q,et al. Tenuigenin
Asian J Psychiatr,2013,6(1):22-28.
promotes proliferation and differentiation of hippocampal
[29] IRVING E A,BARONE F C,REITH A D,et al. Differen-
neural stem cells[J]. Neurochem Res,2012,37(4):771-
tial activation of MAPK/ERK and p38/SAPK in neruones
777.
and glia following focal cerebral ischemia in the rat[J].
[17] DINIZ B S,TEIXEIRA A L. Brain-derived neurotrophic
Brain Res Mol Brain Res,2000,77(1):65-75.
factor and Alzheimer’s disease:physiopathology and be- [30] GUO X,YUAN J,WANG J,et al. Calcitriol alleviates
yond[J]. Neuromolecular Med,2011,13(4):217-222.
global cerebral ischemia-induced cognitive impairment by
[18] WATERHOUSE E G,XU B J. New insights into the role reducing apoptosis regulated by VDR/ERK signaling path-
of brain-derived neurotrophic factor in synaptic plastici- way in rat hippocampus[J]. Brain Res,2019,1724(1):
ty[J].Mol Cell Neurosci,2009,42(2):81-89. 146430.
[19] WU B W,WU M S,GUO J D. Effects of microRNA-10a
(收稿日期:2020-12-14 修回日期:2021-04-20)
on synapse remodeling in hippocampal neurons and neuro- (编辑:邹丽娟)
nal cell proliferation and apoptosis through the BDNF-
·1186 · China Pharmacy 2021 Vol. 32 No. 10 中国药房 2021年第32卷第10期