Page 44 - 《中国药房》2021年第9期
P. 44

[11]  段颖,郭翔宇,孙文,等.番石榴叶提取物调节小鼠脂肪组                    [23]  塞伦,张会志,苏胜偶.回顾与展望肥胖的药物治疗[J].糖
             织 TNF-α、PPAR-γ基因表达改善肝脏糖调节机制研                        尿病天地(临床),2010,4(7):318-327.
             究[J].中华中医药杂志,2014,29(5):1622-1625.             [24]  黄世杰.由于致癌危险美国消协要求奥利司他撤出市
        [12]  国家药典委员会.中华人民共和国药典:一部[S]. 2015年                     场[J].国外医学(药学分册),2006,33(5):328.
             版.北京:中国医药科技出版社,2015:229.                       [25]  王佳黎,姚继红,宁青,等.和厚朴酚纳米混悬剂抑制肝脏
        [13]  张慧娟,龚苏晓,许浚,等.泽泻药材的研究进展及其质量                         糖异生改善高脂饮食小鼠血糖水平的研究[J].药学学
             标志物的预测分析[J].中草药,2019,50(19):4741-4751.              报,2019,54(2):288-293.
        [14]  MENG Q,DUAN X P,WANG C Y,et al. Alisol B 23-ace-  [26]  杨志刚,郑文惠,张凯雪,等.沙棘叶中鞣质类成分及其抗
             tate protects against non-alcoholic steatohepatitis in mice  炎和抗肥胖活性研究 [J].中草药,2019,50(12):2809-
             via farnesoid Ⅹ receptor activation[J]. Acta Pharmacol  2816.
             Sin,2016,38(1):69-79.                          [27]  刘珊珊.泽泻水提物化学成分及产地差异研究[D].北京:
        [15]  AVTANSKI D,PAVLOV V A,TRACEY K J,et al. Cha-       中国中医科学院,2019.
             racterization of inflammation and insulin resistance in  [28]  JIN H G,JIN Q,RYUN KIM A,et al. A new triterpenoid
             high-fat diet-induced male C57BL/6J mouse model of obe-  from Alisma orientale and their antibacterial effect[J].
             sity[J]. Animal Model Exp Med ,2019,2(4):252-258.   Arch Pharm Res,2012,35(11):1919-1926.
        [16]  申瑞玲,马婧.四种肥胖动物造模方法的比较[J].动物医                   [29]  BASTARD J P,MAACHI M,LAGATHU C,et al. Recent
             学进展,2007,28(3):105-108.                             advances in the relationship between obesity,inflamma-
        [17]  MENG Q,CHEN X,WANG C,et al. Protective effects of  tion,and insulin resistance[J]. Eur Cytokine Netw,2006,
             alisol B 23-acetate via farnesoid Ⅹ receptor-mediated re-  17(1):4-12.
             gulation of transporters and enzymes in estrogen-induced  [30]  AJUWON K M,SPURLOCK M E. Palmitate activates
             cholestatic liver injury in mice[J]. Pharm Res,2015,32  the NF-κ B transcription factor and induces IL-6 and
             (11):3688-3698.                                     TNFα expression in 3T3-L1 adipocytes[J]. J Nutr,2005,
        [18]  YE Z,LIU G,GUO L,et al. Hypothalamic endoplasmic   135(8):1841-1846.
             reticulum stress as a key mediator of obesity-induced  [31]  段颖,郭翔宇,孙文,等.番石榴叶提取物调节小鼠脂肪组
             leptin resistance[J]. Obes Rev,2018,19(6):770-785.  织 TNF-α、PPAR-γ基因表达改善肝脏糖调节机制研
        [19]  SINGH G M,DANAEI G,FARZADFAR F,et al. The          究[J].中华中医药杂志,2014,29(5):1622-1625.
             age-specific quantitative effects of metabolic risk factors  [32]  COLVILLE-NASH P,WILLIS D,PAPWORTH J,et al.
             on cardiovascular diseases and diabetes:a pooled analy-  The peroxisome proliferatoractivated receptor alpha acti-
             sis[J]. PLoS One,2013,8(7):e65174.                  vator,Wy14,643,is anti-inflammatory in vivo[J]. Inflam-
        [20]  BALLINGER A,PEILIN S R. Orlistat:its current status  mopharmacology,2005,12(5/6):493-504.
             as an anti-obesity drug[J]. Eur J Pharmacol,2002,440(2/  [33]  PATEL N G,H OLDER J C,SMITH S A,et al. Differen-
             3):109-117.                                         tial regulation of lipogenesis and leptin production by in-
        [21]  ZHI J,MULLIGAN T E,HAUPTMAN J B. Long-term         dependent signaling pathways and rosiglitazone during hu-
             systemic exposure of orlistat,a lipase inhibitor,and its me-  man adipocyte differentiation[J]. Diabetes,2003,52(1):
             tabolites in obese patients[J]. J Clin Pharmacol,1999,39  43-50.
             (1):41-46.                                     [34]  LARSEN T M,TOUBRO S,ASTRUP A. PPAR-γ ago-
        [22]  FINER N,JAMES W P,KOPELMAN P G,et al. One-         nists in the treatment of type2 diabetes:is increased fat-
             year treatment of obesity:a randomized,double-blind,pla-  ness commensurate with long-term efficacy?[J]. Int J
             cebo-controlled,multicentre study of orlistat,a gastroin-  Obes Relat Metab Disord,2003,27(2):147-161.
             testinal lipase inhibitor[J]. Int J Obes Relat Metab Disord,  (收稿日期:2020-12-14  修回日期:2021-02-21)
             2000,24(3):306-313.                                                                 (编辑:唐晓莲)













        ·1062 ·  China Pharmacy 2021 Vol. 32 No. 9                                   中国药房    2021年第32卷第9期
   39   40   41   42   43   44   45   46   47   48   49