Page 118 - 2020年21期

表2 共被引频次排名前10位的文献
Tab 2 Top 10 literatures in the list of co-citation fre-
quency
序号 作者 发表年份 题目 被引频次
1 Radcliff S等 2015 American geriatrics society 2015 updated beers criteria for 301
potentially inappropriate medication use in older adults
2 Fick D等 2012 American geriatrics society updated beers criteria for 290
potentially inappropriate medication use in older adults
3 O’Mahony D等 2015 STOPP/START criteria for potentially inappropriate 267
prescribing in older people：version 2
4 Gnjidic D等 2012 Polypharmacy cutoff and outcomes：five or more medicines 249
were used to identify community-dwelling older men at risk
of different adverse outcomes
5 Maher RL等 2014 Clinical consequences of polypharmacy in elderly 221
6 Scott IA等 2015 Reducing inappropriate polypharmacy：the process of 186
deprescribing
7 Gallagher P等 2008 STOPP （Screening Tool of Older Persons’potentially 161 图5 关键词共现网络关系图谱
inappropriate Prescriptions）：application to acutely ill elderly Fig 5 Relation graph of keywords co-occurrence net-
patients and comparison with Beers’criteria
work
8 Fried TR等 2014 Health outcomes associated with polypharmacy in 124
community-dwelling older adults：a systematic review 进行聚类分析，通过对数拟然率算法（LLR）聚类方式命
9 Garfinkel D等 2010 Feasibility study of a systematic approach for discontinuation 119 名，生成聚类图谱，详见图6。图谱中Modularity Q表示
of multiple medications in older adults： addressing
polypharmacy 网络的模块度（Q 值），取值范围为 0～1（取值越接近 1，
10 Daniel SB等 2011 Emergency hospitalizations for adverse drug events in older 107 即聚类间的联系越紧密，聚类结果越好；Q＞0.3 表明网
Americans
络聚类结构是显著的 ）；图谱中Sihouette 表示轮廓值（S
[9]
表3 共被引中心度排名前10位的文献
值），是衡量网络同质性的指标，取值范围为－1～1（取
Tab 3 Top 10 literatures in the list of co-citation cen-
值越接近1，表示聚类内节点间的联系越紧密，同质性相
trality
对越好，聚类结果可信度越高；S＞0.7 表明聚类效果是
序号 作者 发表年份 题目 中心度
[7]
1 Spinewine A等 2007 Appropriate prescribing in elderly people：how well can it be 0.14 令人信服的 ）。结果得到6个关键词聚类群标签，聚类
measured and optimised?
的 Q＝0.375 7＞0.3，S＝0.699 2＞0.5，说明网络模块结
2 Gnjidic D等 2012 Polypharmacy cutoff and outcomes：five or more medicines 0.11
were used to identify community-dwelling older men at risk 构较为显著，聚类效果良好，同质性较好 [7，9] 。对每一聚
of different adverse outcomes
类的关键词按频次从高到低排序，其聚类及包含的关键
3 Scott IA等 2015 Reducing inappropriate polypharmacy： the process of 0.11
deprescribing 词见表4。
4 Gallagher P等 2008 STOPP （Screening Tool of Older Persons’ potentially 0.11
inappropriate Prescriptions）：application to acutely ill elderly
patients and comparison with Beers’criteria
5 Garfinkel D等 2010 Feasibility study of a systematic approach for discontinuation 0.11
of multiple medications in older adults： addressing
polypharmacy
6 O’Mahony D等 2015 STOPP/START criteria for potentially inappropriate 0.10
prescribing in older people：version 2
7 Gnjidic D等 2012 High-risk prescribing and incidence of frailty among older 0.10
community-dwelling men
8 Hilmer SN等 2009 The effects of polypharmacy in older adults 0.10
9 Barnett K等 2012 Epidemiology of multimorbidity and implications for health 0.09
care，research，and medical education：a cross-sectional study
10 Gallagher PF等 2011 Prevention of potentially inappropriate prescribing for elderly 0.09
patients：a randomized controlled trial using STOPP/START
criteria
通过对热门关键词进行分析，可以推测老年多重用

药的危险因素、健康结局（包括衰弱、住院、死亡）以及对
多重用药的减少策略是目前研究的热点 [25-29] 。 图6 关键词聚类图谱
2.7.2 聚类分析 利用 CiteSpace 5.6.R5 软件对关键词 Fig 6 Clustering graph of keywords

·2668 · China Pharmacy 2020 Vol. 31 No. 21 中国药房 2020年第31卷第21期