Page 145 - 《中国药房》2026年1期
P. 145
[ 3 ] OH P J,LEE J R,KIM S K,et al. Changes in ronal uptake transporters contribute to oxaliplatin neuro‐
chemotherapy-induced peripheral neuropathy,disturbance toxicity in mice[J]. J Clin Invest,2020,130(9):4601-
in activities of daily living,and depression following che‐ 4606.
motherapy in patients with colorectal cancer:a prospec‐ [17] YI Y D,LI L P,SONG F F,et al. L-tetrahydropalmatine
tive study[J]. Eur J Oncol Nurs,2020,44:101676. reduces oxaliplatin accumulation in the dorsal root gang-
[ 4 ] ZHANG C Y,XU C,GAO X Y,et al. Platinum-based lion and mitochondria through selectively inhibiting the
drugs for cancer therapy and anti-tumor strategies[J]. Thera- transporter-mediated uptake thereby attenuates peripheral
nostics,2022,12(5):2115-2132. neurotoxicity[J]. Toxicology,2021,459:152853.
[ 5 ] VALÉRY M,TANGUY M L,GELLI M,et al. Oxaliplatin- [18] 鲁琼,朱海宏,戚听听,等. OCTN2 基因多态性影响结直
induced peripheral neuropathy with hepatic arterial versus 肠癌奥沙利铂化疗敏感性[J]. 中国临床药理学与治疗
intravenous infusion in metastatic colorectal cancer[J]. 学,2021,26(4):401-407.
Support Care Cancer,2024,32(10):660. [19] 陈佳音,王丽,王立军,等. 有机阳离子转运体基因多态
[ 6 ] 刘素,张侠. 奥沙利铂神经毒性机制及基因多态性研究 性与奥沙利铂毒性及疗效的相关性研究[J]. 中国临床药
进展[J]. 中华临床医师杂志,2015,9(9):1685-1689. 理学与治疗学,2022,27(2):171-177.
[ 7 ] TAÏB S, DURAND J, BRUNET I. Neuropathie [20] VARGAS-ALIAGA A,DE LA HABA M,CONTRERAS
périphérique induite par l’oxaliplatine:comment faire M J,et al. NeuroPredict:study of the predictive value of
barrière?[J]. Médecine,2020,36:33-37. ABCB1 genetic polymorphisms and associated clinical
[ 8 ] BABACAN A. Cold-associated laryngopharyngeal dyses‐ factors in chronic chemotherapy-induced peripheral neu‐
thesia syndrome after oxaliplatin treatment[J]. J Oncol ropathy (CIPN)[J]. Front Pharmacol,2024,15:1352939.
Pharm Pract,2024,30(7):1245-1248. [21] DIONISI M,RIVA B,DELCONTI M,et al. Inhibition of
[ 9 ] BRANCA J J V,CARRINO D,GULISANO M,et al. NHE1 transport activity and gene transcription in DRG
Oxaliplatin-induced neuropathy:genetic and epigenetic neurons in oxaliplatin-induced painful peripheral neuro‐
profile to better understand how to ameliorate this side ef‐ toxicity[J]. Sci Rep,2023,13(1):3991.
fect[J]. Front Mol Biosci,2021,8:643824. [22] KIM W,CHO Y A,KIM D C,et al. Association between
[10] KAWASHIRI T,MINE K,KOBAYASHI D,et al. Thera‐ genetic polymorphism of GSTP1 and toxicities in patients
peutic agents for oxaliplatin-induced peripheral neuropa‐ receiving platinum-based chemotherapy:a systematic re‐
thy; experimental and clinical evidence[J]. Int J Mol Sci, view and meta-analysis[J]. Pharmaceuticals (Basel),
2021,22(3):1393. 2022,15(4):439.
[11] TENG C,COHEN J,EGGER S,et al. Systematic review [23] CERPA L C,SANDOVAL C,ESCALANTE P,et al. Ge‐
of long-term chemotherapy-induced peripheral neuropathy netic variants and clinical determinants affecting the re‐
(CIPN) following adjuvant oxaliplatin for colorectal can‐ sponse to 5-fluorouracil-based treatment in Chilean pa‐
cer[J]. Support Care Cancer,2022,30(1):33-47. tients with advanced colorectal cancer[J]. Front Oncol,
[12] EGASHIRA N. Pathological mechanisms and preventive 2025,15:1589724.
strategies of oxaliplatin-induced peripheral neuropathy[J]. [24] CHEN Y C,TZENG C H,CHEN P M,et al. Influence of
Front Pain Res (Lausanne),2021,2:804260. GSTP1 I105V polymorphism on cumulative neuropathy
[13] IBRAHIM E Y, EHRLICH B E. Prevention of and outcome of FOLFOX-4 treatment in Asian patients
chemotherapy-induced peripheral neuropathy:a review of with colorectal carcinoma[J]. Cancer Sci,2010,101(2):
recent findings[J]. Crit Rev Oncol Hematol,2020,145: 530-535.
102831. [25] 曲珍,徐圣秋,王轩 . GSTP1 基因多态性与结直肠癌患
[14] NICHETTI F,FALVELLA F S,MICELI R,et al. Is a 者奥沙利铂化疗敏感性及周围神经毒性的关系[J]. 肿瘤
pharmacogenomic panel useful to estimate the risk of 药学,2023,13(4):449-454.
oxaliplatin-related neurotoxicity in colorectal cancer pa‐ [26] PUERTA-GARCÍA E,URBANO-PÉREZ D,CARRASCO-
tients?[J]. Pharmacogenomics J,2019,19(5):465-472. CAMPOS M I,et al. Effect of DPYD,MTHFR,ABCB1,
[15] GALLUCCIO M,TRIPICCHIO M,POCHINI L. The hu‐ XRCC1,ERCC1 and GSTP1 on chemotherapy related
man OCTN sub-family:gene and protein structure,expres‐ toxicity in colorectal carcinoma[J]. Surg Oncol,2020,35:
sion,and regulation[J]. Int J Mol Sci,2024,25(16):8743. 388-398.
[16] HUANG K M,LEBLANC A F,UDDIN M E,et al. Neu‐ [27] VELASCO R,ALEMANY M,VILLAGRÁN M,et al.
中国药房 2026年第37卷第1期 China Pharmacy 2026 Vol. 37 No. 1 · 135 ·

