Page 138 - 《中国药房》2025年6期
P. 138

[19]  SONG W,PATEL A,QURESHI H Y,et al. The Parkinson’s   regulation  of  DJ-1  and  Nrf2/HO-1  pathways  in  a  rodent
               disease-associated A30P  mutation  stabilizes  alpha-synuclein   model of Parkinson’s disease[J]. Trop J Pharm Res,2021,
               against  proteasomal  degradation  triggered  by  heme        18(5):1017-1025.
               oxygenase-1  over-expression  in  human  neuroblastoma   [30]  SHAH S,PUSHPA TRYPHENA K,SINGH G,et al. Neu‐
               cells[J]. J Neurochem,2009,110(2):719-733.          roprotective role of carvacrol via Nrf2/HO-1/NLRP3 axis
          [20]  ZUKOR H,SONG W,LIBERMAN A,et al. HO-1-media-       in rotenone-induced PD mice model[J]. Brain Res,2024,
               ted  macroautophagy:a  mechanism  for  unregulated  iron    1836:148954.
               deposition  in  aging  and  degenerating  neural  tissues[J].  J   [31]  ZHANG J Y,BAI Q Y,WEN Q T,et al. Paeoniflorin pro‐
               Neurochem,2009,109(3):776-791.                      tects  1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-
          [21]  CAO  Q  Q,ZOU  Q  M,ZHAO  X,et  al.  Regulation  of   induced Parkinson’s disease mice by inhibiting oxidative
               BDNF  transcription  by  Nrf2  and  MeCP2  ameliorates   stress and neuronal apoptosis through activating the Nrf2/
               MPTP-induced neurotoxicity[J]. Cell Death Discov,2022,  HO-1  signaling  pathway[J].  Neuroreport,2023,34(5):
               8(1):267.                                           255-266.
          [22]  HUNG  S  Y,LIOU  H  C,FU  W  M.  The  mechanism  of   [32]  BALUCHNEJADMOJARAD   T,  RABIEE   N,
               heme oxygenase-1 action involved in the enhancement of   ZABIHNEJAD S,et al. Ellagic acid exerts protective ef‐
               neurotrophic  factor  expression[J].  Neuropharmacology,  fect  in  intrastriatal  6-hydroxydopamine  rat  model  of
               2010,58(2):321-329.                                 Parkinson’s  disease:possible  involvement  of  ERβ/Nrf2/
          [23]  HU K,ZHU S S,WU F Y,et al. Aureusidin ameliorates 6-  HO-1 signaling[J]. Brain Res,2017,1662:23-30.
               OHDA-induced  neurotoxicity  via  activating  Nrf2/HO-1   [33]  ZHAO Y,HAN Y J,WANG Z H,et al. Rosmarinic acid
               signaling   pathway   and   preventing   mitochondria-  protects  against  1-methyl-4-phenyl-1,2,3,6-tetrahy-
               dependent  apoptosis  pathway  in  SH-SY5Y  cells  and      dropyridine-induced dopaminergic neurotoxicity in zebrafish
               Caenorhabditis  elegans[J].  Chem  Biol  Interact,2024,  embryos[J]. Toxicol In Vitro,2020,65:104823.
               387:110824.                                    [34]  REN Y,YE  D,DING Y  P,et  al.  Ginsenoside  RK1  pre‐
          [24]  LAI X Y,ZHANG Y J,WU J N,et al. Rutin attenuates   vents  1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-
               oxidative  stress  via  PHB2-mediated  mitophagy  in  MPP -  induced Parkinson’s disease via activating silence infor‐
                                                         +
               induced SH-SY5Y cells[J]. Neurotox Res,2023,41(3):  mation regulator 3-mediated Nrf2/HO-1 signaling pathway
               242-255.                                            [J]. Hum Exp Toxicol,2023,42:9603271231220610.
          [25]  ZHOU H,MAO Z,ZHANG X N,et al. Neuroprotective   [35]  HUANG J Y,YUAN Y H,YAN J Q,et al. 20C,a biben‐
               effect of mangiferin against Parkinson’s disease through   zyl  compound  isolated  from  Gastrodia  elata,protects
               G-protein-coupled  receptor-interacting  protein  1(GIT1)-    PC12 cells against rotenone-induced apoptosis via activa‐
               mediated  antioxidant  defense[J].  ACS  Chem  Neurosci,  tion  of  the  Nrf2/ARE/HO-1  signaling  pathway[J].  Acta
               2023,14(8):1379-1387.                               Pharmacol Sin,2016,37(6):731-740.
          [26]  HE D W,FU S P,ZHOU A,et al. Camptothecin regulates   [36]  潘涛,肖琪,樊慧杰,等 . 五子衍宗丸通过调控 Keap-1/
               microglia  polarization  and  exerts  neuroprotective  effects   Nrf2/HO-1 通路保护帕金森病小鼠神经元[J/OL]. 解放
               via activating Akt/Nrf2/HO-1 and inhibiting NF-κB path‐  军 医 学 杂 志 ,2023(2023-10-11)[2024-09-14].  https://
               ways  in  vivo  and  in  vitro[J].  Front  Immunol,2021,12:  link.cnki.net/urlid/11.1056.R.20231009.0852.002.
               619761.                                             PAN T,XIAO Q,FAN H J,et al. Wuzi yanzong pill pro‐
          [27]  张玲玉,何长宏,赵忠正,等 . 青藤碱调节 GSK3β/Nrf2/                  tects  neurons  of  Parkinson’s  disease  mice  by  regulating
               HO-1及NF-κB信号通路对帕金森病小鼠的神经保护作                         Keap-1/Nrf2/HO-1  pathway[J/OL].  J  Med  Chin  PLA,
               用[J]. 中药新药与临床药理,2024,35(5):607-614.                 2023(2023-10-11)[2024-09-14].  https://link. cnki. net/
               ZHANG L Y,HE C H,ZHAO Z Z,et al. Neuroprotective    urlid/11.1056.R.20231009.0852.002.
               effect of sinomenine on Parkinson’s disease mice by regu‐  [37]  赵贝贝,郑春叶,雒晓东,等 . 帕病 2 号方对帕金森病模
               lating GSK3β/Nrf2/HO-1 and NF-κB signaling pathways  型大鼠中脑黑质Nrf2,HO-1表达的影响[J]. 中国实验方
               [J]. Tradit Chin Drug Res Clin Pharmacol,2024,35(5):  剂学杂志,2014,20(8):158-162.
               607-614.                                            ZHAO B B,ZHENG C Y,LUO X D,et al. Research on
          [28]  ZHANG C X,ZHOU J Y,ZHUO L X,et al. The TLR4/       expressions of Nrf2 and HO-1 in substantia nigra of rats
               NF-κB/NLRP3 and Nrf2/HO-1 pathways mediate the neu‐  with  Parkinson’s  disease  treated  with  Pabing  2  formula
               roprotective  effects  of  alkaloids  extracted  from  Uncaria   [J].  Chin  J  Exp  Tradit  Med  Formulae,2014,20(8):
               rhynchophylla in Parkinson’s disease[J]. J Ethnopharma‐  158-162.
               col,2024,333:118391.                                         (收稿日期:2024-09-24  修回日期:2024-10-22)
          [29]  ZHANG J Z,WANG Y H,JI X W,et al. Tanshinone ⅡA                                    (编辑:李 劲)
               protects  against  dopaminergic  neuron  degeneration  via


          · 768 ·    China Pharmacy  2025 Vol. 36  No. 6                               中国药房  2025年第36卷第6期
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