Page 138 - 《中国药房》2024年24期
P. 138
sis in target cells[J]. Science,2020,368(6494):eaaz7548. mediated pyroptosis in diabetic nephropathy[J]. Exp Cell
[19] ZHANG Z B,ZHANG Y,XIA S Y,et al. Gasdermin E Res,2020,396(2):112293.
suppresses tumour growth by activating anti-tumour im‐ [30] WEN S,DENG F,LI L L,et al. VX-765 ameliorates renal
munity[J]. Nature,2020,579(7799):415-420. injury and fibrosis in diabetes by regulating caspase-1-me‐
[20] DENG W Y,BAI Y,DENG F,et al. Streptococcal pyro‐ diated pyroptosis and inflammation[J]. J Diabetes Investig,
genic exotoxin B cleaves GSDMA and triggers pyroptosis 2022,13(1):22-33.
[J]. Nature,2022,602(7897):496-502. [31] JIA Y,XU H,YU Q,et al. Identification and verification
[21] CHENG Q,PAN J,ZHOU Z L,et al. Caspase-11/4 and of vascular cell adhesion protein 1 as an immune-related
gasdermin D-mediated pyroptosis contribute to podocyte Hub gene associated with the tubulointerstitial injury in
injury in mouse diabetic nephropathy[J]. Acta Pharmacol diabetic kidney disease[J]. Bioengineered,2021,12(1):
Sin,2021,42(6):954-963. 6655-6673.
[22] ZUO Y,CHEN L,HE X Y,et al. Atorvastatin regulates [32] CHEN W J,WANG J L,LUO Y,et al. Ginsenoside Rb1
MALAT1/miR-200c/NRF2 activity to protect against and compound K improve insulin signaling and inhibit ER
podocyte pyroptosis induced by high glucose[J]. Diabetes stress-associated NLRP3 inflammasome activation in adi‐
Metab Syndr Obes,2021,14:1631-1645. pose tissue[J]. J Ginseng Res,2016,40(4):351-358.
[23] ZHU W,LI Y Y,ZENG H X,et al. Carnosine alleviates [33] TIAN Y C,FENG X Y,ZHOU Z M,et al. Ginsenoside
podocyte injury in diabetic nephropathy by targeting cas‐ compound K ameliorates osteoarthritis by inhibiting the
pase-1-mediated pyroptosis[J]. Int Immunopharmacol, chondrocyte endoplasmic reticulum stress-mediated
2021,101(Pt. B):108236. IRE1α-TXNIP-NLRP3 axis and pyroptosis[J]. J Agric Food
[24] LI F T,CHEN Y,LI Y J,et al. Geniposide alleviates dia‐ Chem,2023,71(3):1499-1509.
betic nephropathy of mice through AMPK/SIRT1/NF-κB [34] WEI Y G,YANG H X,ZHU C H,et al. Ginsenoside Rg5
pathway[J]. Eur J Pharmacol,2020,886:173449. relieves type 2 diabetes by improving hepatic insulin resis‐
[25] CHEN S J,LV L L,LIU B C,et al. Crosstalk between tu‐ tance in db/db mice[J]. J Funct Foods,2020,71:104014.
bular epithelial cells and glomerular endothelial cells in [35] ZHU Y Y,ZHU C H,YANG H X,et al. Protective effect
diabetic kidney disease[J]. Cell Prolif,2020,53(3): of ginsenoside Rg5 against kidney injury via inhibition of
e12763. NLRP3 inflammasome activation and the MAPK signa-
[26] 温洁,高颖颖 . 银杏素调节 NF-κB/NLRP3/Caspase-1 信 ling pathway in high-fat diet/streptozotocin-induced dia‐
号通路对高糖诱导肾小球内皮细胞焦亡的影响[J]. 河北 betic mice[J]. Pharmacol Res,2020,155:104746.
医药,2023,45(15):2251-2255,2260. [36] HAN Y L,SU Y,HAN M,et al. Ginsenoside Rg1 attenua-
WEN J,GAO Y Y. Ginkgo biloba extract regulates high- tes glomerular fibrosis by inhibiting CD36/TRPC6/NFAT2
glucose-induced pyroptosis in glomerular endothelial cells signaling in type 2 diabetes mellitus mice[J]. J Ethnophar‐
by mediating the NF-κB/NLRP3/Caspase-1 signaling macol,2023,302(Pt. A):115923.
pathway[J]. Hebei Med J,2023,45(15):2251-2255,2260. [37] WANG T,GAO Y B,YUE R C,et al. Ginsenoside Rg1
[27] SHEN Y L,CHEN W,LIN K H,et al. Notoginsenoside alleviates podocyte injury induced by hyperlipidemia via
Fc,a novel renoprotective agent,ameliorates glomerular targeting the mTOR/NF-κB/NLRP3 axis[J]. Evid Based
endothelial cells pyroptosis and mitochondrial dysfunction Complement Alternat Med,2020,2020:2735714.
in diabetic nephropathy through regulating HMGCS2 path‐ [38] 滕杰,陈业刚 . 人参皂苷 Rg1 抑制 NLRP3/Caspase-1 通
way[J]. Phytomedicine,2024,126:155445. 路抵抗肾纤维化的作用研究[J]. 天津医科大学学报,
[28] 吕佳,郝亚宁,王晓培,等. 骨髓间充质干细胞来源外泌 2023,29(4):398-405.
体 miR-30e-5p 改善高血糖诱发的肾小管上皮细胞的焦 TENG J,CHEN Y G. Effect of ginsenoside Rg1 on inhibi‐
亡 [J]. 西 安 交 通 大 学 学 报(医 学 版),2023,44(6): tion of NLRP3/Caspase-1 pathway against renal fibrosis
859-865. [J]. J Tianjin Med Univ,2023,29(4):398-405.
LYU J,HAO Y N,WANG X P,et al. Bone marrow me- [39] ZHANG R R,GUAN S,MENG Z Q,et al. Ginsenoside
senchymal stem cell-derived exosomal miR-30e-5p amelio- Rb1 alleviates 3-MCPD-induced renal cell pyroptosis by
rates high-glucose induced renal proximal tubular cell activating mitophagy[J]. Food Chem Toxicol,2024,186:
pyroptosis[J]. J Xi’an Jiaotong Univ Med Sci,2023,44 114522.
(6):859-865. (收稿日期:2024-07-10 修回日期:2024-12-07)
[29] KE R Q,WANG Y,HONG S H,et al. Endoplasmic reticu‐ (编辑:胡晓霖)
lum stress related factor IRE1α regulates TXNIP/NLRP3-
· 3092 · China Pharmacy 2024 Vol. 35 No. 24 中国药房 2024年第35卷第24期