Page 138 - 《中国药房》2024年13期
P. 138
ruxolitinib shows effective in treating myelofibrosis[J]. controlled,phase 2 trial[J]. Lancet,2020,396(10244):
Ann Hematol,2021,100(1):135-141. 110-120.
[12] MOYO T K,KISHTAGARI A,VILLAUME M T,et al. [24] ROSMARIN D,PASSERON T,PANDYA A G,et al. Two
PI3K inhibition restores and amplifies response to ruxoli‐ phase 3,randomized,controlled trials of ruxolitinib cream
tinib in patients with myelofibrosis[J]. Clin Cancer Res, for vitiligo[J]. N Engl J Med,2022,387(16):1445-1455.
2023,29(13):2375-2384. [25] LAUGHTER M R,MAYMONE M B C,MASHAYEKHI S,
[13] KUYKENDALL A T. Treatment of hydroxyurea-resistant/ et al. The global burden of atopic dermatitis:lessons from
intolerant polycythemia vera:a discussion of best practices the global burden of disease study 1990-2017[J]. Br J
[J]. Ann Hematol,2023,102(5):985-993. Dermatol,2021,184(2):304-309.
[14] BEWERSDORF J P,HOW J,MASAROVA L,et al. [26] FREITAS E,GOODERHAM M,TORRES T. New topical
Moving toward disease modification in polycythemia vera therapies in development for atopic dermatitis[J]. Drugs,
[J]. Blood,2023,142(22):1859-1870. 2022,82(8):843-853.
[15] VERSTOVSEK S,PASSAMONTI F,RAMBALDI A, [27] OWJI S,CALDAS S A,UNGAR B. Management of
et al. A phase 2 study of ruxolitinib,an oral JAK1 and atopic dermatitis:clinical utility of ruxolitinib[J]. J
JAK2 inhibitor,in patients with advanced polycythemia Asthma Allergy,2022,15:1527-1537.
vera who are refractory or intolerant to hydroxyurea[J]. [28] BISSONNETTE R,CALL R S,RAOOF T,et al. A
Cancer,2014,120(4):513-520. maximum-use trial of ruxolitinib cream in adolescents and
[16] VANNUCCHI A M,KILADJIAN J J,GRIESSHAMMER adults with atopic dermatitis[J]. Am J Clin Dermatol,
M,et al. Ruxolitinib versus standard therapy for the treat‐ 2022,23(3):355-364.
ment of polycythemia vera[J]. N Engl J Med,2015,372 [29] KIM B S,SUN K,PAPP K,et al. Effects of ruxolitinib
(5):426-435. cream on pruritus and quality of life in atopic dermatitis:
[17] XU C,LEI Z X,WANG L,et al. The effect of transplanta‐ results from a phase 2,randomized,dose-ranging,vehicle-
tion of cultured autologous melanocytes on CXCL9, and active-controlled study[J]. J Am Acad Dermatol,
CXCL10 and CXCL11 expressions in vitiligo[J]. Indian J 2020,82(6):1305-1313.
Dermatol,2023,68(4):486. [30] KING B,KO J,FORMAN S,et al. Efficacy and safety of
[18] KUBELIS-LÓPEZ D E,ZAPATA-SALAZAR N A,SAID- the oral Janus kinase inhibitor baricitinib in the treatment
FERNÁNDEZ S L,et al. Updates and new medical treat‐ of adults with alopecia areata:phase 2 results from a ran‐
ments for vitiligo (review)[J]. Exp Ther Med,2021,22 domized controlled study[J]. J Am Acad Dermatol,2021,
(2):797. 85(4):847-853.
[19] WU J,SMOGORZEWSKI J. Off-label studies on ruxoli‐ [31] DAINICHI T,IWATA M,KAKU Y. Alopecia areata:
tinib in dermatology:a review[J]. J Dermatolog Treat, what’s new in the diagnosis and treatment with JAK in‐
2022,33(2):606-612. hibitors?[J]. J Dermatol,2024,51(2):196-209.
[20] SHEIKH A,RAFIQUE W,OWAIS R,et al. FDA ap‐ [32] OLSEN E A,KORNACKI D,SUN K,et al. Ruxolitinib
proves ruxolitinib (Opzelura) for vitiligo therapy:a break‐ cream for the treatment of patients with alopecia areata:a
through in the field of dermatology[J]. Ann Med Surg, 2-part, double-blind, randomized, vehicle-controlled
2022,81:104499. phase 2 study[J]. J Am Acad Dermatol,2020,82(2):
[21] ROTHSTEIN B,JOSHIPURA D,SARAIYA A,et al. 412-419.
Treatment of vitiligo with the topical Janus kinase inhibi‐ [33] BAYART C B,DENIRO K L,BRICHTA L,et al. Topical
tor ruxolitinib[J]. J Am Acad Dermatol,2017,76(6): Janus kinase inhibitors for the treatment of pediatric alope‐
1054-1060.e1. cia areata[J]. J Am Acad Dermatol,2017,77(1):167-170.
[22] KOHLI I,VEENSTRA J,HAMZAVI I. Vitiligo assess‐ [34] ALMUTAIRI N,NOUR T M,HUSSAIN N H. Janus ki‐
ment methods:Vitiligo Area Scoring Index and Vitiligo nase inhibitors for the treatment of severe alopecia areata:
European Task Force assessment[J]. Br J Dermatol,2015, an open-label comparative study[J]. Dermatology,2019,
172(2):318-319. 235(2):130-136.
[23] ROSMARIN D,PANDYA A G,LEBWOHL M,et al. (收稿日期:2023-11-02 修回日期:2024-06-20)
Ruxolitinib cream for treatment of vitiligo:a randomized, (编辑:胡晓霖)
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