Page 137 - 《中国药房》2023年19期
P. 137

疗治疗胰腺癌的用药规律分析[J]. 世界科学技术-中医                    [17]  SHAO  Q  L,ZHANG  Z  Q,CAO  R  X,et  al.  CPA4  pro‐
              药现代化,2021,23(10):3719-3726.                         motes  EMT  in  pancreatic  cancer  via  stimulating  PI3K-
              HUANG R,ZHANG P T,LI F J. Analysis of medication    AKT-mTOR  signaling[J].  Onco  Targets  Ther,2020,13:
              regularity of traditional Chinese medicine decoction com‐  8567-8580.
              bined  with  chemotherapy  in  the  treatment  of  pancreatic   [18]  SHI  S  Q,CAO  H  M.  Shikonin  promotes  autophagy  in
              cancer based on data mining[J]. Mod Tradit Chin Med Ma‐  BXPC-3 human pancreatic cancer cells through the PI3K/
              ter Med World Sci Technol,2021,23(10):3719-3726.    Akt signaling pathway[J]. Oncol Lett,2014,8(3):1087-
          [ 6 ]  ZHANG Y Q,KWOK-SHING NG P,KUCHERLAPATI           1089.
              M,et al. A pan-cancer proteogenomic atlas of PI3K/Akt/  [19]  KONG L M,LIU P,ZHENG M J,et al. The miR-1224-5p/
              mTOR pathway alterations[J]. Cancer Cell,2017,31(6):  ELF3 axis regulates malignant behaviors of pancreatic can‐
              820-832.e3.                                         cer via PI3K/Akt/Notch signaling pathways[J]. Onco Tar‐
          [ 7 ]  EMMANOUILIDI A,FYFFE C A,FERRO R,et al. Pre‐     gets Ther,2020,13:3449-3466.
              clinical  validation  of  3-phosphoinositide-dependent  pro‐  [20]  ZHANG  Y  N,CHEN  D  Y,ZHANG  G  Q,et  al.  mi‐
              tein kinase 1 inhibition in pancreatic cancer[J]. J Exp Clin   croRNA-23b-3p  promotes  pancreatic  cancer  cell  tumori‐
              Cancer Res,2019,38(1):191.                          genesis and metastasis via the JAK/PI3K and Akt/NF-κB
          [ 8 ]  刘光宇,王琦,苏玲. 多糖类成分抗胰腺癌作用机制的研                       signaling pathways[J]. Oncol Lett,2020,20(5):160.
              究进展[J]. 中国药房,2023,34(1):111-116.               [21]  陈伟毅,秦春宏,陈延,等. 青藤碱通过调控PI3K/Akt通
              LIU G Y,WANG Q,SU L. Research progress on the ef‐   路介导的上皮间质转化抑制胰腺癌AsPC-1细胞侵袭和
              fect mechanism of polysaccharides against pancreatic can‐  转移[J]. 中国现代应用药学,2022,39(11):1419-1425.
              cer[J]. China Pharm,2023,34(1):111-116.             CHEN W Y,QIN C H,CHEN Y,et al. Sinomenine inhi-
          [ 9 ]  LIU J L,XU P G,LIU D K,et al. TCM regulates PI3K/  bits the invasion and metastasis of pancreatic adenocarci‐
              Akt signal pathway to intervene atherosclerotic cardiovas‐  noma AsPC-1  cells  by  inhibiting  epithelial  mesenchymal
              cular  disease[J].  Evid  Based  Complement Alternat  Med,  transition mediated by PI3K/Akt pathway[J]. Chin J Mod
              2021,2021:4854755.                                  Appl Pharm,2022,39(11):1419-1425.
          [10]  HE Y,SUN M M,ZHANG G G,et al. Targeting PI3K/  [22]  ZHANG Z Q,XUAN W L,HUANG Y,et al. Dictamnine
              Akt  signal  transduction  for  cancer  therapy[J].  Signal   inhibits  pancreatic  cancer  cell  growth  and  epithelial-
              Transduct Target Ther,2021,6(1):425.                mesenchymal transition by blocking the PI3K/Akt signa-
          [11]  LONG H Z,CHENG Y,ZHOU Z W,et al. PI3K/Akt sig‐    ling pathway[J]. Neoplasma,2022,69(3):603-619.
              nal pathway:a target of natural products in the prevention   [23]  张 珦 ,范 竞 ,章 宜 芬 ,等 .  蝙 蝠 葛 碱 抑 制 人 胰 腺 癌
              and treatment of Alzheimer’s disease and Parkinson’s di-   SW1900 细胞系增殖及诱导其凋亡[J]. 解剖学报,2020,
              sease[J]. Front Pharmacol,2021,12:648636.           51(4):543-547.
          [12]  DENG S,LEONG H C,DATTA A,et al. PI3K/Akt signa-   ZHANG X,FAN J,ZHANG Y F,et al. Dauricine inhibi-
              ling tips the balance of cytoskeletal forces for cancer pro‐  ting the cell proliferation and inducing the cell apoptosis
              gression[J]. Cancers,2022,14(7):1652.               of  human  pancreatic  cancer  cells  line  SW1900[J].  Acta
          [13]  LU Y,ZHOU X Y,ZHOU C L,et al. Insulin receptor ty‐  Anat Sin,2020,51(4):543-547.
              rosine  kinase  substrate (IRTKS)  promotes  the  tumorige-   [24]  田龙夫,张琦,王波涛,等. 血根碱通过调控PI3K/Akt信
              nesis of pancreatic cancer via PI3K/Akt signaling[J]. Hum   号通路诱导胰腺癌细胞凋亡的机制[J]. 中国实验方剂学
              Cell,2022,35(6):1885-1899.                          杂志,2018,24(19):166-171.
          [14]  ZHU Y,KE  J T,GONG Y  J,et  al. A  genetic  variant  in   TIAN L F,ZHANG Q,WANG B T,et al. Mechanism of
              PIK3R1  is  associated  with  pancreatic  cancer  survival  in   sanguinarine  in  inducing  apoptosis  in  murine  pancreatic
              the Chinese population[J]. Cancer Med,2019,8(7):3575-  cancer cells by inhibiting PI3K/Akt signaling pathway[J].
              3582.                                               Chin J Exp Tradit Med Formulae,2018,24(19):166-171.
          [15]  MASSIHNIA D,AVAN A,FUNEL N,et al. Phospho-Akt   [25]  OKUNO K,XU C M,PASCUAL-SABATER S,et al. Ber‐
              overexpression is prognostic and can be used to tailor the   berine  overcomes  gemcitabine-associated  chemoresis‐
              synergistic interaction of Akt inhibitors with gemcitabine   tance  through  regulation  of  Rap1/PI3K-Akt  signaling  in
              in pancreatic cancer[J]. J Hematol Oncol,2017,10(1):9.  pancreatic  ductal  adenocarcinoma[J].  Pharmaceuticals,
          [16]  FALEIRO  I,ROBERTO  V  P,DEMIRKOL  CANLI  S,      2022,15(10):1199.
              et  al.  DNA  methylation  of  PI3K/Akt  pathway-related   [26]  HONG Z,WANG Z H,ZHOU B,et al. Effects of evodi‐
              genes predicts outcome in patients with pancreatic cancer:  amine on PI3K/Akt and MAPK/ERK signaling pathways
              a comprehensive bioinformatics-based study[J]. Cancers,  in  pancreatic  cancer  cells[J].  Int  J  Oncol,2020,56(3):
              2021,13(24):6354.                                   783-793.


          中国药房  2023年第34卷第19期                                              China Pharmacy  2023 Vol. 34  No. 19    · 2431 ·
   132   133   134   135   136   137   138   139   140