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参考文献 with polymyxin resistance in carbapenem-resistant
[ 1 ] NORDMANN P，CUZON G，NAAS T. The real threat of Klebsiella pneumoniae in Brazil[J]. Mem Inst Oswaldo
Klebsiella pneumoniae carbapenemase-producing bacteria Cruz，2019，114：e180555.
[J]. Lancet Infect Dis，2009，9（4）：228-236. [15] TSENG T S，TU I F，CHEN H T，et al. Protein-DNA com-
[ 2 ] BISWAS S，BRUNEL J M，DUBUS J C，et al. Colistin：an plex-guided discovery of the antibacterial lead E1 for re-
update on the antibiotic of the 21st century[J]. Expert Rev storing the susceptibility of Klebsiella Pneumoniae to
Anti Infect Ther，2012，10（8）：917-934. polymyxin B by targeting the response regulator PmrA[J].
[ 3 ] AH Y M，KIM A J，LEE J Y. Colistin resistance in Kleb- Chem Commun（Camb），2018，54（49）：6372-6375.
siella pneumoniae[J]. Int J Antimicrob Agents，2014，44 [16] KONG Y Y，LI C，CHEN H F，et al. In vivo emergence of
（1）：8-15. colistin resistance in carbapenem-resistant Klebsiella
[ 4 ] HANCOCK R E. Peptide antibiotics[J]. Lancet，1997，349 pneumoniae mediated by premature termination of the
（9049）：418-422. mgrB gene regulator[J]. Front Microbiol，2021，12：
[ 5 ] EL-SAYED AHMED M A E，ZHONG L L，SHEN C，et al. 656610.
Colistin and its role in the Era of antibiotic resistance：an [17] CANNATELLI A，GIANI T，D’ANDREA M M，et al.
extended review：2000-2019[J]. Emerg Microbes Infect， MgrB inactivation is a common mechanism of colistin re-
2020，9（1）：868-885. sistance in KPC-producing Klebsiella pneumoniae of clini-
[ 6 ] LI Z F，VELKOV T. Polymyxins：mode of action[J]. Adv cal origin[J]. Antimicrob Agents Chemother，2014，58
Exp Med Biol，2019，1145：37-54. （10）：5696-5703.
[ 7 ] SIERRA J M，FUSTÉ E，RABANAL F，et al. An overview [18] KATO A，GROISMAN E A. Connecting two-component
of antimicrobial peptides and the latest advances in their regulatory systems by a protein that protects a response
development[J]. Expert Opin Biol Ther，2017，17（6）： regulator from dephosphorylation by its cognate sensor[J].
663-676. Genes Dev，2004，18（18）：2302-2313.
[ 8 ] FRESNO S，JIMÉNEZ N，IZQUIERDO L，et al. The ionic [19] WRIGHT M S，SUZUKI Y，JONES M B，et al. Genomic
interaction of Klebsiella pneumoniae K2 capsule and core and transcriptomic analyses of colistin-resistant clinical
lipopolysaccharide[J]. Microbiology（Reading），2006，152 isolates of Klebsiella pneumoniae reveal multiple path-
（Pt 6）：1807-1818. ways of resistance[J]. Antimicrob Agents Chemother，
[ 9 ] SHERRY N，HOWDEN B. Emerging Gram negative resis- 2015，59（1）：536-543.
tance to last-line antimicrobial agents fosfomycin，colistin [20] LIU Y Y，WANG Y，WALSH T R，et al. Emergence of
and ceftazidime-avibactam - epidemiology，laboratory de- plasmid-mediated colistin resistance mechanism MCR-1
tection and treatment implications[J]. Expert Rev Anti In- in animals and human beings in China：a microbiological
fect Ther，2018，16（4）：289-306. and molecular biological study[J]. Lancet Infect Dis，
[10] OLAITAN A O，MORAND S，ROLAIN J M. Mecha- 2016，16（2）：161-168.
nisms of polymyxin resistance：acquired and intrinsic [21] DU H，CHEN L，TANG Y W，et al. Emergence of the
resistance in bacteria[J]. Front Microbiol，2014，5：643. mcr-1 colistin resistance gene in carbapenem-resistant
[11] CHENG Y H，LIN T L，LIN Y T，et al. Amino acid substi- Enterobacteriaceae[J]. Lancet Infect Dis，2016，16（3）：
tutions of CrrB responsible for resistance to colistin 287-288.
through CrrC in Klebsiella pneumoniae[J]. Antimicrob [22] WANG X M，WANG Y，ZHOU Y，et al. Emergence of a
Agents Chemother，2016，60（6）：3709-3716. novel mobile colistin resistance gene，mcr-8，in NDM-pro-
[12] ELIAS R，DUARTE A，PERDIGÃO J. A molecular per- ducing Klebsiella pneumoniae[J]. Emerg Microbes Infect，
spective on colistin and Klebsiella pneumoniae：mode of 2018，7（1）：122.
action，resistance genetics，and phenotypic susceptibility [23] DI PILATO V，ARENA F，TASCINI C，et al. Mcr-1.2，a
[J]. Diagnostics（Basel），2021，11（7）：1165. new mcr variant carried on a transferable plasmid from a
[13] JAYOL A，POIREL L，BRINK A，et al. Resistance to colis- colistin-resistant KPC carbapenemase-producing Klebsiella
tin associated with a single amino acid change in protein pneumoniae strain of sequence type 512[J]. Antimicrob
PmrB among Klebsiella pneumoniae isolates of world- Agents Chemother，2016，60（9）：5612-5615.
wide origin[J]. Antimicrob Agents Chemother，2014，58 [24] AHMED Z S，ELSHAFIEE E A，KHALEFA H S，et al.
（8）：4762-4766. Evidence of colistin resistance genes（mcr-1 and mcr-2）
[14] RODRIGUES A C S，SANTOS I C O，CAMPOS C C， in wild birds and its public health implication in Egypt[J].
et al. Non-clonal occurrence of pmrB mutations associated Antimicrob Resist Infect Control，2019，8：197.

中国药房 2022年第33卷第17期 China Pharmacy 2022 Vol. 33 No. 17 ·2175 ·