Page 138 - 《中国药房》2021年第4期
P. 138
phys Res Commun,2018,494(1/2):165-172. longumine-directed anticancer agents by an electrophilici-
[19] THONGSOM S,SUGINTA W,LEE KJ,et al. Piperlongu- ty-based prooxidant strategy:a mechanistic investiga-
mine induces G2/M phase arrest and apoptosis in cholan- tion[J]. Free Radic Biol Med,2016. DOI:10.1016/j.fre-
giocarcinoma cells through the ROS-JNK-ERK signaling eradbiomed.2016.05.021.
pathway[J]. Apoptosis,2017,22(11):1473-1484. [29] ZHANG Y,MA H,WU Y,et al. Novel non-trimethoxyl-
[20] 陈宙,陈春雷,林晖,等.荜茇酰胺对人胆管癌 HCCC- phenyl piperlongumine derivatives selectively kill cancer
9810细胞增殖和凋亡的影响[J].广东医学院学报,2016, cells[J]. Bioorg Med Chem Lett,2017,27(11):2308-
34(5):484-486、490. 2312.
[21] SOMCHAI S,YONOWAPA S,THEERA S,et al.(-)-Ku- [30] GONG LH,CHEN XX,WANG H,et al. Piperlongumine
sunokinin and piperloguminine from piper nigrum:an al- induces apoptosis and synergizes with cisplatin or pacli-
ternative option to treat breast cancer[J]. Biomed Pharma- taxel in human ovarian cancer cells[J]. Oxid Med Cell
cother,2017. DOI:10.1016/j.biopha.2017.05.130. Longev,2014. DOI:10.1155/2014/906804.
[22] 肖楠,姚建新,徐党辉,等.荜茇酰胺对人肺腺癌A549细 [31] PUNGANURU SR,MADALA HR,VENUGOPAL SN,
胞的增殖及其辐射敏感性的影响[J].山西医药杂志, et al. Design and synthesis of a C7-aryl piperlongumine
2017,46(11):1259-1262. derivative with potent antimicrotubule and mutant p53-re-
[23] 肖楠,徐党辉,潘志尧,等.荜茇酰胺对人肺腺癌A549细 activating properties[J]. Eur J Med Chem,2016. DOI:
胞辐射敏感性的影响[J].山东医药,2017,57(6):13-16. 10.1016/j.ejmech.2015.10.052.
[24] CHEN YJ,KUO CC,TING LL,et al. Pipeilongumine in- [32] WU Y,MIN X,ZHUANG H,et al. Design,synthesis and
hibits cancer stem cell properties and regulates multiple biological activity of piperlongumine derivatives as selec-
malignant phenotypes in oral cancer[J]. Oncol Lett,2018, tive anticancer agents[J]. Eur J Med Chem,2014. DOI:
15(2):1789-1798. 10.1016/j.ejmech.2014.05.070.
[25] ZOU Y,YAN C,ZHANG H,et al. Synthesis and evalua- [33] MEEGAN MJ,NATHWANI S,TWAMLEY B,et al.
tion of N-heteroaromatic ring-based analogs of piperlong- Piperlongumine(piplartine)and analogues:antiprolifera-
umine as potent anticancer agents[J]. Eur J Med Chem, tive microtubule-destabilising agents[J]. Eur J Med Chem,
2017. DOI:10.1016/j.ejmech.2017.06.046. 2017,125:453-463.
[26] LAD NP,KULKARNI S,SHARMA R,et al. Piperlongu- [34] LIAO Y,NIU X,CHEN B,et al. Synthesis and antileuke-
mine derived cyclic sulfonamides(sultams):synthesis and mic activities of piperlongumine and HDAC inhibitor hy-
in vitro exploration for therapeutic potential against Hela brids against acute myeloid leukemia cells[J]. J Med
cancer cell lines[J]. Eur J Med Chem,2017. DOI:10.1016/ Chem,2016,59(17):7974-7990.
j.ejmech.2016.12.022. [35] XU X,FANG X,WANG J,et al. Identification of novel
[27] ADAMS DJ,DAI M,PELLEGRINO G,et al. Synthesis, ROS induce by merging the fragments of piperlongumine
cellular evaluation,and mechanism of action of piperlong- and dicoumarol[J]. Bioorg Med Chem Lett,2017,27(5):
umine analogs[J]. Proc Natl Acad Sci U S A,2012,109 1325-1328.
(38):15115-15120. (收稿日期:2020-10-14 修回日期:2020-12-30)
[28] YAN WJ,WANG Q,YUAN CH,et al. Designing piper- (编辑:罗 瑞)
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