Page 138 - 202011
P. 138
效及毒性作用的研究进展[J].中国新药杂志,2008,17 [39] FUJITA K,SUGIURA T,OKUMURA H,et al. Direct in-
(15):1298-1302. hibition and down-regulation by uremic plasma compo-
[26] SANTOS A,ZANETTA S,CRESTEIL T,et al. Metabo- nents of hepatic uptake transporter for SN-38,an active
lism of irinotecan(CPT-11)by CYP3A4 and CYP3A5 in metabolite of irinotecan,in humans[J]. Pharm Res,2014,
humans[J]. Clin Cancer Res,2000,6(5):2012-2020. 31(1):204-215.
[27] DODDS HM,HAAZ MC,RIOU JF,et al. Identification [40] NIEMI M,PASANEN MK,NEUVONEN PJ. Organic an-
of a new metabolite of CPT-11(irinotecan):pharmacolog- ion transporting polypeptide 1B1:a genetically polymor-
ical properties and activation to SN-38[J]. J Pharmacol phic transporter of major importance for hepatic drug up-
Exp Ther,1998,286(1):578-583. take[J]. Pharmacol Rev,2011,63(1):157-181.
[28] MATHIJSSEN RH,DE JONG FA,VAN SCHAIK RH, [41] PASANEN MK,NEUVONEN PJ,NIEMI M. Global anal-
et al. Prediction of irinotecan pharmacokinetics by use of ysis of genetic variation in SLCO1B1[J]. Pharmacoge-
cytochrome P450 3A4 phenotyping probes[J]. J Natl Can- nomics,2008,9(1):19-33.
cer Inst,2004,96(21):1585-1592. [42] XU LY,HE YJ,ZHANG W,et al. Organic anion transport-
[29] RIERA P,SALAZAR J,VIRGILI AC,et al. Relevance of ing polypeptide-1B1 haplotypes in Chinese patients[J]. Ac-
CYP3A4*20,UGT1A1*37 and UGT1A1*28 variants in ta Pharmacol Sin,2007,28(10):1693-1697.
irinotecan-induced severe toxicity[J]. Br J Clin Pharma- [43] TAKANE H,MIYATA M,BURIOKA N,et al. Severe tox-
col,2018,84(6):1389-1392. icities after irinotecan-based chemotherapy in a patient
[30] DEAN M,RZHETSKY A,ALLIKMETS R. The human with lung cancer:a homozygote for the SLCO1B1*15 al-
ATP-binding cassette(ABC)transporter superfamily[J]. lele[J]. Ther Drug Monit,2007,29(5):666-668.
Genome Res,2001,11(7):1156-1166. [44] TAKANE H,KAWAMOTO K,SASAKI T,et al. Life-
[31] 李雪轻,瞿全新. ABC 转运体与卵巢癌耐药关系的研究 threatening toxicities in a patient with UGT1A1*6/*28
进展[J].国际妇产科学杂志,2009,36(2):131-134. and SLCO1B1*15/*15 genotypes after irinotecan-based
[32] SALVADOR-MARTÍN S,GARCÍA-GONZÁLEZ X,GA- chemotherapy[J]. Cancer Chemother Pharmacol,2009,63
RCÍA MI,et al. Clinical utility of ABCB1 genotyping for (6):1165-1169.
preventing toxicity in treatment with irinotecan[J]. Phar- [45] SAKAGUCHI S,GARCIA-BOURNISSEN F,KIM R,
macol Res,2018. DOI:10.1016/j.phrs.2018.08.026. et al. Prolonged neutropenia after irinotecan-based chemo-
[33] CHEN S,VILLENEUVE L,JONKER D,et al. ABCC5 therapy in a child with polymorphisms of UGT1A1 and
and ABCG1 polymorphisms predict irinotecan-induced se- SLCO1B1[J]. Arch Dis Child,2009,94(12):981-982.
vere toxicity in metastatic colorectal cancer patients[J]. [46] TEFT WA,WELCH S,LENEHAN J,et al. OATP1B1 and
Pharmacogenet Genomics,2015,25(12):573-583. tumour OATP1B3 modulate exposure,toxicity,and sur-
[34] DE MATTIA E,TOFFOLI G,POLESEL J,et al. Pharma- vival after irinotecan-based chemotherapy[J]. Br J Can-
cogenetics of ABC and SLC transporters in metastatic cer,2015,112(5):857-865.
colorectal cancer patients receiving first-line FOLFIRI [47] HUANG L,ZHANG T,XIE C,et al. SLCO1B1 and
treatment[J]. Pharmacogenet Genomics,2013,23(10): SLC19A1 gene variants and irinotecan-induced rapid re-
549-557. sponse and survival:a prospective multicenter pharmaco-
[35] TRUMPI K,EMMINK BL,PRINS AM,et al. ABC-trans- genetics study of metastatic colorectal cancer[J]. PLoS
porter expression does not correlate with response to irino- One,2013. DOI:10.1371/journal.pone.0077223.
tecan in patients with metastatic colorectal cancer[J]. J [48] TREENERT A,AREEPIUM N,TANASANVIMON S. Ef-
Cancer,2015,6(11):1079-1086. fects of ABCC2 and SLCO1B1 polymorphisms on treat-
[36] HAGENBUCH B,MEIER PJ. The superfamily of organic ment responses in Thai metastatic colorectal cancer pa-
anion transporting polypeptides[J]. Biochim Biophys Acta, tients treated with irinotecan-based chemotherapy[J].
2003,1609(1):1-18. Asian Pac J Cancer Prev,2018,19(10):2757-2764.
[37] 万子睿,谢海棠,郭栋,等.焦磷酸测序技术检测 SL- [49] 中国临床肿瘤学会指南工作委员会.中国临床肿瘤学会
CO1B1基因多态性方法的建立[J].中国临床药理学与治 (CSCO)结直肠癌诊疗指南2019[M]. 北京:人民卫生出
疗学,2012,17(5):543-548. 版社,2019:72-73.
[38] GONG IY,KIM RB. Impact of genetic variation in OATP (收稿日期:2019-10-28 修回日期:2020-03-31)
transporters to drug disposition and response[J]. Drug (编辑:张元媛)
Metab Pharmacokinet,2013,28(1):4-18.
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