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态;可通过多靶点协同作用发挥选择性抗肿瘤效应;可 [10] LIU C L,CHIU Y T,HU M L. Fucoxanthin enhances HO-1
通过调控肠道菌群、β3ADR/UCP-1信号通路等发挥抗肥 and NQO1 expression in murine hepatic BNL CL.2 cells
胖作用。另外,岩藻黄素的特征性官能团具有良好的靶 through activation of the Nrf2/ARE system partially by its
点选择性和可逆抑制活性,是新型药物设计开发的 pro-oxidant activity[J]. J Agric Food Chem,2011,59
模板。 (20):11344-11351.
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有相关研究文献发表,然而该成分的产业化、商业化开
inhibiting ferroptosis via Nrf2/STAT3 and glutathione
发仍处于起步阶段 ,这可能与岩藻黄素的性能研究不
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足以及生产工艺开发中遇到的难题(如生产工艺成本
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高、绿色可持续性低)有关。已有研究在硅藻中探索岩
GLOBOCAN 2022 cancer estimates:data sources,me-
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藻黄素的合成路径 ,未来或可通过生物合成技术,解
thods,and a snapshot of the cancer burden worldwide[J].
决岩藻黄素的生产难题。
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中国药房 2025年第36卷第17期 China Pharmacy 2025 Vol. 36 No. 17 · 2219 ·

