Page 138 - 《中国药房》2025年7期
P. 138
adipocyte and lipid metabolism[J]. Food Funct,2020,11 lecular mechanisms of cell death:recommendations of the
(1):483-492. nomenclature committee on cell death 2018[J]. Cell Death
[12] BALKRISHNA A,GOHEL V,SINGH R,et al. Livogrit Differ,2018,25(3):486-541.
ameliorates acetaldehyde-induced steatosis in HepG2 cells [25] 刘英琦,施喆,孙树刚,等. 澳洲茄碱通过MAPK/ERK信
through modulation of lipogenesis and β-oxidation path‐ 号通路调控肝癌细胞增殖、迁移和侵袭的研究[J]. 中国
ways[J]. Phytomed Plus,2021,1(3):100067. 医院用药评价与分析,2023,23(2):182-186.
[13] CHOI J W,CHOI H J,RYU G H,et al. Inhibition of lipid [26] ZHU L N,LU Y,SUN Z,et al. The application of an
droplet accumulation by Solanum nigrum by suppressing aqueous two-phase system combined with ultrasonic cell
adipogenesis and inducing lipolysis,thermogenesis and disruption extraction and HPLC in the simultaneous sepa‐
autophagy in 3T3-L1 cells[J]. Exp Ther Med,2023,26 ration and analysis of solanine and Solanum nigrum poly‐
(1):333. saccharide from Solanum nigrum unripe fruit[J]. Food
[14] JAVED T,ASHFAQ U A,RIAZ S,et al. In-vitro antiviral Chem,2020,304:125383.
activity of Solanum nigrum against Hepatitis C virus[J]. [27] NAWAZ A,JAMAL A,ARIF A,et al. In vitro cytotoxic
Virol J,2011,8:26. potential of Solanum nigrum against human cancer cell
[15] 吴晶晶,张文娟,张骏鸿,等 . 澳洲茄边碱对人肝癌 lines[J]. Saudi J Biol Sci,2021,28(8):4786-4792.
[28] LIN L T,CHOONG C Y,TAI C J. Solanine attenuates
HepG2 细胞生长和凋亡的影响及机制初探[J]. 中国药
hepatocarcinoma migration and invasion induced by
房,2021,32(24):2963-2969.
acetylcholine[J]. Integr Cancer Ther,2020,19:15347354-
[16] 刘良裕. 中药龙葵、白英的甾体生物碱类成分及抗肿瘤
20909895.
作用研究[D]. 北京:中国中医科学院,2022.
[29] 杨旭峰. 从调控TGF-β/Smads通路途径探讨龙葵防治肝
[17] LIU L Y,YANG Y K,WANG J N,et al. Steroidal alka‐
癌的机理[J]. 陕西中医,2017,38(5):549-551.
loids from Solanum nigrum and their cytotoxic activities
[30] YANG M Y,HUNG C H,CHANG C H,et al. Solanum
[J]. Phytochemistry,2022,202:113317.
nigrum suppresses angiogenesis-mediated tumor growth
[18] LUYEN B T T,TRANG B T T. New solasodine-type gly‐
through inhibition of the AKT/mTOR pathway[J]. Am J
coalkaloids isolated from Solanum nigrum and their cyto‐
Chin Med,2016,44(6):1273-1288.
toxic activity[J]. Chem Biodivers,2024,21 (7) :
[31] AKSHATHA G M,RAVAL S K,ARPITHA G M,et al.
e202400872.
Immunohistochemical,histopathological study and chemo‐
[19] 姚譞 . 中药龙葵活性成分抗肿瘤药效及作用机制研究
protective effect of Solanum nigrum in N-nitroso
[D]. 上海:上海中医药大学,2020.
diethylamine-induced hepatocellular carcinoma in Wistar
[20] NATH L R,GORANTLA J N,THULASIDASAN A K T,
rats[J]. Vet World,2018,11(4):402-409.
et al. Evaluation of uttroside B,a saponin from Solanum
[32] 高聚伟,徐凯,冉冉,等. 龙葵碱对肝癌Treg细胞介导的
nigrum Linn,as a promising chemotherapeutic agent
肿瘤免疫逃逸的影响[J]. 中国现代医生,2021,59(18):
against hepatocellular carcinoma[J]. Sci Rep,2016,6:
35-38,42,193.
36318.
[33] 杨旭峰,温钱杏,张晶锐 . 龙葵片防治肝癌的临床研究
[21] NATH L R,SWETHA M,VIJAYAKURUP V,et al.
[J]. 中西医结合肝病杂志,2017,27(6):353-355.
Blockade of uttroside B-induced autophagic pro-survival
[34] 徐振杰,管静. 龙葵承气汤对肝癌介入术后患者并发症
signals augments its chemotherapeutic efficacy against he‐
及肝功能的影响[J]. 新中医,2015,47(8):207-209.
patocellular carcinoma[J]. Front Oncol,2022,12:812598. [35] 黄东彬,管静 . 龙葵承气汤对原发性肝癌患者 TACE 术
[22] KEERTHANA C K,AISWARYA S U,RAYGINIA T P, 后肝纤维化指标及免疫功能的影响[J]. 新中医,2016,48
et al. A novel combinatorial regimen using sorafenib and (5):211-213.
uttroside B,a US FDA-designated ‘orphan drug’,for the [36] 张玲,曾健,李军,等. 软肝化纤汤治疗慢性乙型肝炎肝
treatment of hepatocellular carcinoma[J]. Anticancer 纤维化患者 50 例临床观察[J]. 中华中医药杂志,2016,
Agents Med Chem,2024,24(19):1431-1441. 31(12):5382-5385.
[23] WANG H C,CHUNG P J,WU C H,et al. Solanum [37] 张团结. 软肝化纤汤联合恩替卡韦治疗慢性乙型肝炎后
nigrum L. polyphenolic extract inhibits hepatocarcinoma 肝纤维化(肝郁脾虚)随机平行对照研究[J]. 实用中医内
cell growth by inducing G2/M phase arrest and apoptosis 科杂志,2019,33(4):32-35.
[J]. J Sci Food Agric,2011,91(1):178-185. (收稿日期:2024-09-10 修回日期:2025-02-17)
[24] GALLUZZI L,VITALE I,AARONSON S A,et al. Mo‐ (编辑:胡晓霖)
· 896 · China Pharmacy 2025 Vol. 36 No. 7 中国药房 2025年第36卷第7期