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·药物与临床·

        基于VOSviewer软件的黄芪治疗糖尿病研究文献计量分析                                                             Δ


        马 斌 ,柴 智 ,王金虹(1.山西中医药大学健康服务与管理学院,太原 030619;2.山西中医药大学黄芪资
                                 1
                        2 #
               1*
        源产业化及产业国际化协同创新中心,太原 030619)
        中图分类号 R195;G353          文献标志码 A           文章编号 1001-0408(2020)21-2634-06
        DOI   10.6039/j.issn.1001-0408.2020.21.13

        摘   要   目的:为直观便捷地了解黄芪治疗糖尿病的研究重点提供数据参考。方法 :检索2000年1月1日-2020年6月30日中
        国知网全文数据库中收录的关于黄芪治疗糖尿病相关文献,采用文献计量学方法,对文献发表数量、发文作者及其研究方向、关键
        词、研究机构分布情况、来源期刊分布情况、被引频次、基金资助等内容进行统计分析,并使用 VOSviewer软件进行可视化展示。
        结果:共纳入文献 2 960篇,文献数量大体呈现增长趋势;发文量最高的作者是辽宁中医药大学的范颖,研究方向主要为黄芪不同
        有效部位对糖尿病模型动物血清胰岛素、脂联素的影响等;关键词词频中,糖尿病肾病(845次)、黄芪(615次)、糖尿病(587次)、黄
        芪注射液(350次)、糖尿病周围神经病变(303)、补气药(202次)等出现频次较高;发文量超过 20 篇的机构有10所,其中南京中医
        药大学发文最多(58篇);《陕西中医》《中国中西医结合肾病杂志》《内蒙古中医药》是发文量较多的期刊;陈国辉等发表的《黄芪的
        化学成分及药理作用研究进展》被引频次最高,为690次;国家级科研基金(包括国家自然科学基金和国家重点基础研究发展计划
        等)资助项目较多。结论:我国近20年来黄芪治疗糖尿病研究水平稳步提高,但是文献分布不均衡,高质量核心期刊发文量较少,
        且相关临床试验相对较少。笔者建议研究人员应从宏观临床疗效、微观药理学、黄芪遗传资源库、中医经典方剂等角度探索黄芪
        治疗糖尿病的方法和思路。
        关键词     黄芪;糖尿病;黄芪多糖;可视化分析;文献计量学;VOSviewer

        Bibliometric Analysis of Astragalus membranaceus in the Treatment of Diabetes Based on VOSviewer
        Software
        MA Bin ,CHAI Zhi ,WANG Jinhong(1. School of Health Service and Management,Shanxi University of
                1
                                           1
                           2
        TCM,Taiyuan 030619, China; 2. Astragalus Resource Industrialization and Industrial Internationalization
        Collaborative Innovation Center,Shanxi University of TCM,Taiyuan 030619,China)

        ABSTRACT    OBJECTIVE:To provide reference for intuitively and conveniently cognizing the research focus of Astragalus
        membranaceus in the treatment of diabetes. METHODS:Using the method of bibliometrics,the literatures about the treatment of
        diabetes by A. membranaceus were retrieved from CNKI full-text database during Jan. 1st,2000-Jun. 30th,2020. Bibliometric
        method was used to statistically analyze the number of articles,authors and their research directions,keywords,distribution of
        research institutions,source journals,frequency of citations,fund funding,etc. VOSviewer software was used for visual display.
        RESULTS:A total of 2 960 literatures were included,and the number of literatures showed an increasing trend;the author with
        the most literatures was Fan Ying from Liaoning University of TCM,whose research direction was the effect of different effective
        parts of A. membranaceus on serum insulin and adiponectin in diabetic animal models;in the keyword frequency analysis,diabetic
        nephropathy(845 times),A. membranaceus(615 times),diabetes(587 times),A. membranaceus injection(350 times),diabetic
        peripheral neuropathy(303 times),qi tonifying drug(202 times)were hot topics. There were 10 institutions with more than 20
        literatures,of which Nanjing University of TCM has published the most literatures(58 pieces). Shaanxi Journal of Traditional
        Chinese Medicine,Chinese Journal of Integrated Traditional and Western Nephropathy and Inner Mongolia Journal of Traditional
                                                            Chinese Medicine were the journals with a large number of
            Δ 基金项目:国家重点研发计划项目课题(No.2019YFC1710801);         literatures;Research Progress on Chemical Constituents and
        山西省重点研发计划项目(No.201803D31091);山西省重点研发计划
                                                            Pharmacological  Effects  of  Astragalus  membranaceus
        重点项目(No.201603D3111001);山西省高等学校科技创新计划(No.
                                                            published from Chen guohui and others was cited most
        2020L0441);山西省中医科研课题(No.2020YYC013);山西省黄芪资
                                                            frequently,for 690 times;there are many projects funded by
        源产业化及产业国际化协同创新中心项目(No.HQXTCXZX 2016-
                                                            national scientific research funds (including National Natural
        016);山西中医药大学科技创新能力培育计划项目(No.2019PY-033)
            *副教授,硕士。研究方向:医药信息处理和数据挖掘。电话:                    Science Foundation of China and the National Key Basic
        0351-3179915。E-mail:mbsxtcm@163.com                 Research Special Foundation of China). CONCLUSIONS:In
            # 通信作者:教授,博士。研究方向:方药药效及其作用机制。电                  the past 20 years, the level of researches about A.
        话:0351-3179952。E-mail:chaizhi@sxtcm.edu.cn          membranaceus in the treatment of diabetes have been steadily


        ·2634 ·  China Pharmacy 2020 Vol. 31 No. 21                                 中国药房    2020年第31卷第21期
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