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中医药治疗慢性湿疹的研究进展
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          张 霞 ,饶志粒,刘 霞,沈 萍,王 琴(重庆中医药学院附属第一医院/重庆市中医院药剂科,重庆
                                                 #
          400021)

          中图分类号  R965      文献标志码  A      文章编号  1001-0408(2026)06-0817-06
          DOI  10.6039/j.issn.1001-0408.2026.06.21


          摘  要  慢性湿疹在我国有着较高的发病率,严重影响患者生活质量。中医药凭借辨证论治与整体观念的独特优势,通过内外兼
          治的方式,在慢性湿疹的治疗中得以广泛应用,并在缓解病情、降低复发率、维持病情稳定、提升患者生活质量等方面表现出了良
          好的效果和独特的优势。其中,内服中药(如加味龙胆泻肝汤)可通过整体调节来改善患者症状;外用中药可借助熏洗、溻渍、膏剂
          等药物疗法直接作用于皮损部位,亦可结合针刺、艾灸、穴位埋线、刺络拔罐等非药物疗法有效缓解相关临床症状;此外,中药内服
          联合外用、多种外治法整合及中西医结合等特色治疗方案在调节免疫功能、减轻皮损及瘙痒症状等方面亦表现出一定优势,这些
          疗法相互配合,形成内外同治的协同效应。建议未来开展更多高质量、大样本临床研究,系统证实中医药的治疗优势并深入探讨
          其发挥作用的具体分子机制。
          关键词  中医药;慢性湿疹;内服;外治;中西医结合

          Research progress of traditional Chinese medicine in the treatment of chronic eczema

          ZHANG Xia,RAO Zhili,LIU Xia,SHEN Ping,WANG Qin(Dept. of Pharmacy, the First Affiliated Hospital of
          Chongqing  University  of  Chinese  Medicine/Chongqing  Traditional  Chinese  Medicine  Hospital,  Chongqing
          400021, China)

          ABSTRACT   Chronic  eczema  has  a  high  prevalence  in  China,  significantly  impacting  patients’  quality  of  life.  Leveraging  the
          unique  advantages  of  pattern  identification/syndrome  differentiation  and  treatment,  along  with  a  holistic  approach,  traditional
          Chinese medicine (TCM), which integrates internal and external therapies, has been widely applied in the management of chronic
          eczema.  It  has  demonstrated  significant  efficacy  and  distinctive  strengths  in  alleviating  symptoms,  reducing  recurrence  rates,
          maintaining  disease  stability,  and  enhancing  patients’  quality  of  life.  Oral  administration  of  TCM(e.g.  modified  Longdan  xiegan
          decoction)  can  improve  patients’  clinical  symptoms  through  systemic  regulation.  External  use  of TCM  can  directly  act  on  the  skin
          lesion  with  the  help  of  steaming  and  washing,  hydropathic  compress,  ointment  and  other  forms.  At  the  same  time,  it  can
          effectively  relieve  the  clinical  symptoms  of  chronic  eczema  by  combining  with  non-drug  therapies  such  as  acupuncture,
          moxibustion,  acupoint  catgut  embedding,  blood-letting  puncture  and  cupping.  In  addition,  characteristic  therapies  such  as  oral
          administration  of  TCM  combined  with  external  treatment,  a  combination  of  various  external  treatments  and  a  combination  of
          Chinese  and  Western  medicine  have  also  demonstrated  certain  advantages  in  regulating  immune  function,  alleviating  skin  lesions,
          and  relieving  itching  symptoms.  These  therapies  cooperate  with  each  other,  creating  a  synergistic  effect  that  treats  both  the
          symptoms  and  the  root  cause  simultaneously.  It  is  suggested  that  more  high-quality,  large-scale  clinical  research  should  be
          conducted  in  the  future  to  systematically  confirm  the  therapeutic  advantages  of  TCM  and  further  explore  the  specific  molecular
          mechanism of action.
          KEYWORDS    traditional Chinese medicine; chronic eczema; oral administration; external treatment; combination of Chinese and
          Western medicine


                                                                 慢性湿疹(chronic eczema,CE)由急性湿疹、亚急性
             Δ  基金项目 国 家 自 然 科 学 基 金 青 年 科 学 基 金 项 目(No.
          82304833)                                          湿疹反复发作不愈转化而成,是皮肤科常见炎症性皮肤
             *第一作者 中药师,硕士。研究方向:中药药效、中药药理与毒理                  疾病之一 。我国 CE 发病率高,一般人群患病率约为
                                                                     [1]
          学研究。E-mail:2447369208@qq.com
                                                                 [2]
                                                                                              [3]
                                                             7.5% ,儿童患病率为 7.22%~20.64% 。CE 临床表现
             # 通信作者 主任中药师,博士。研究方向:中药药理与新药研发。
          E-mail:wqin1127@cdutcm.edu.cn                      以皮肤苔藓样变为主,患部皮肤呈浸润性暗红斑,常附
          中国药房  2026年第37卷第6期                                                 China Pharmacy  2026 Vol. 37  No. 6    · 817 ·
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